Valérie Deckert Selected Research

Phospholipid Transfer Proteins

1/2022	New therapeutic horizons for plasma phospholipid transfer protein (PLTP): Targeting endotoxemia, infection and sepsis.
4/2018	Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease.
1/2018	PhosphoLipid transfer protein (PLTP) exerts a direct pro-inflammatory effect on rheumatoid arthritis (RA) fibroblasts-like-synoviocytes (FLS) independently of its lipid transfer activity.
1/2017	Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis.
11/2016	Plasma phospholipid transfer protein (PLTP) modulates adaptive immune functions through alternation of T helper cell polarization.
9/2013	Development of abdominal aortic aneurysm is decreased in mice with plasma phospholipid transfer protein deficiency.
4/2013	Increased amyloid-β peptide-induced memory deficits in phospholipid transfer protein (PLTP) gene knockout mice.
4/2011	Worsening of diet-induced atherosclerosis in a new model of transgenic rabbit expressing the human plasma phospholipid transfer protein.
7/2008	Effect of plasma phospholipid transfer protein deficiency on lethal endotoxemia in mice.
11/2007	Cholesterol accumulation is increased in macrophages of phospholipid transfer protein-deficient mice: normalization by dietary alpha-tocopherol supplementation.

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Valérie Deckert Research Topics

Disease

13	Inflammation (Inflammations) 01/2022 - 07/2008
9	Atherosclerosis 01/2021 - 06/2004
5	Endotoxemia 01/2022 - 07/2008
4	Sepsis (Septicemia) 01/2022 - 05/2014
3	Coinfection 01/2021 - 01/2017
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022 - 01/2017
2	Infections 01/2022 - 01/2021
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 01/2019
2	Alzheimer Disease (Alzheimer's Disease) 04/2018 - 04/2013
2	Atherosclerotic Plaque (Atheroma) 12/2009 - 06/2004
1	Bacterial Infections (Bacterial Infection) 01/2022
1	Cholangitis 01/2022
1	Peritonitis 01/2021
1	Shock 01/2021
1	Non-alcoholic Fatty Liver Disease 10/2020
1	Colitis 10/2020
1	Fibrosis (Cirrhosis) 10/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2020
1	Obesity 01/2019
1	Gliosis 04/2018
1	Osteoarthritis 01/2018
1	Rheumatic Diseases (Rheumatism) 01/2018
1	Rheumatoid Arthritis 01/2018
1	Ischemia 10/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017
1	Dyslipidemias (Dyslipidemia) 01/2017
1	Contact Dermatitis (Eczema, Contact) 11/2016
1	Diabetes Mellitus 12/2015
1	Type 2 Diabetes Mellitus (MODY) 12/2015
1	Insulin Resistance 12/2015
1	Cohen syndrome 12/2015
1	Gram-Negative Bacterial Infections 07/2015
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 05/2014
1	Hyperinsulinism (Hyperinsulinemia) 02/2014
1	Abdominal Aortic Aneurysm 09/2013
1	Multiple Trauma (Multiple Injuries) 04/2013
1	Wounds and Injuries (Trauma) 04/2013
1	Memory Disorders (Memory Loss) 04/2013
1	Amyloid Plaque 04/2013
1	Critical Illness (Critically Ill) 04/2013
1	Pathologic Processes 04/2013
1	Melanoma (Melanoma, Malignant) 09/2010
1	Neoplasms (Cancer) 09/2010

Drug/Important Bio-Agent (IBA)

11	Lipoproteins (Lipoprotein)IBA 01/2022 - 02/2005
10	Phospholipid Transfer ProteinsIBA 01/2022 - 11/2007
8	LipidsIBA 01/2022 - 02/2005
8	LipopolysaccharidesIBA 01/2021 - 02/2014
6	CholesterolIBA 01/2022 - 04/2011
3	CytokinesIBA 01/2021 - 01/2018
3	Cholesterol Ester Transfer ProteinsIBA 01/2021 - 02/2005
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 04/2013
2	HDL LipoproteinsIBA 01/2022 - 11/2007
2	Lipopolysaccharide ReceptorsIBA 01/2021 - 01/2019
2	Dextrans (Dextran)FDA Link 10/2020 - 10/2017
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 10/2020 - 10/2017
2	Amyloid (Amyloid Fibrils)IBA 04/2018 - 04/2013
2	Glucagon-Like Peptide 1 (GLP 1)IBA 10/2017 - 02/2014
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 12/2015
2	Glucose (Dextrose)FDA LinkGeneric 12/2015 - 02/2014
2	Vitamin E FDA LinkGeneric 04/2013 - 02/2005
2	AntioxidantsIBA 04/2013 - 11/2002
2	ApolipoproteinsIBA 10/2011 - 12/2009
1	Triglycerides (Triacylglycerol)IBA 01/2022
1	InterferonsIBA 01/2022
1	Apolipoprotein C-I (Apolipoprotein C1)IBA 01/2021
1	EndotoxinsIBA 01/2021
1	CarbonIBA 01/2021
1	human APOC1 proteinIBA 01/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 10/2020
1	InterleukinsIBA 10/2020
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 10/2020
1	NF-kappa B (NF-kB)IBA 10/2020
1	Interleukin-10 (Interleukin 10)IBA 10/2020
1	Plant ExtractsIBA 01/2019
1	PolyphenolsIBA 01/2019
1	OxidesIBA 01/2019
1	EnzymesIBA 04/2018
1	Neprilysin (Neutral Endopeptidase)IBA 04/2018
1	Hormones (Hormone)IBA 10/2017
1	IncretinsIBA 10/2017
1	Glucagon-Like Peptides (Enteroglucagon)IBA 10/2017
1	DinitrofluorobenzeneIBA 11/2016
1	Insulin (Novolin)FDA Link 12/2015
1	Pancreatic Elastase (Elastase)IBA 09/2013
1	Angiotensin IIIBA 09/2013
1	Peptides (Polypeptides)IBA 04/2013
1	LDL Receptors (LDL Receptor)IBA 10/2011
1	Constitutive Androstane ReceptorIBA 10/2011
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 10/2011
1	Apolipoproteins B (ApoB)IBA 04/2011
1	Lipid AIBA 09/2010
1	Apolipoproteins E (ApoE)IBA 12/2009

Therapy/Procedure

2	Punctures 01/2021 - 11/2020
2	Ligation 01/2021 - 11/2020
1	Cell Transplantation 01/2022
1	Kidney Transplantation 01/2019
1	Transplantation 01/2019
1	Injections 01/2017
1	Anesthesia 05/2014
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 05/2014